If you are coming by MBTA’s public transportation:
Impact Hub Boston is a 5-10 minute walk from the Red, Green, Blue, Orange, and Silver Line MTBA.

Park Street station for the Red line and Green line – 8 minute walk northeast on Tremont Street, southeast on Bromfield, northeast on Washington Street, and east on Milk Street.

State Street station for the Blue line and Orange line – 1 minute walk from the Devonshire Street exit.

Downtown Crossing station for the Red line and Silver line (SL5 Temple Pl @ Washington St) – 6 minute walk northeast on Washington Street and east on Milk Street.

If you are driving:
Street parking will probably be competitive in this part of Boston, but if you’re looking to drive, there are a number of parking garages in downtown Boston. Nearby suggestions include 33 Arch Street Garage, the garage at Post Office Square, and La Paz Parking at 1 Post Office Square.